bioengineering Archives - Revolution Bioengineering

Tag Archives: bioengineering

23 Jan

Bioengineering Dragons, Part II – Design

In Part I we talked about the rationale for bioengineering a dragon.

After a healthy and instructive discussion about your dragon needs, it turns out that you mainly want one because it’s cool (and maybe you want to impress your friends a little). Louboutin, Ferrari, Cartier, they are all products that exist primarily to meet this need. In this case, the product is a living creature and I think it is important to reiterate that we must have an ongoing and continuous conversation about the ethics involved.

It also turns out you are ludicrously wealthy and able to fund this project in perpetuity because that’s approximately how long it’s going to take to make you a dragon.

dragon-resting-head-on-womans-lap-31
Cuddly doesn’t always mean fluffy. A 1912 drawing of a lap dragon by R. Leinweber

***

Bioengineering multicellular organisms is expensive. It’s time consuming. It can be a huge investment of resources and people, and very often the way you thought biology worked is only the most surface layer of function, adding years on to your research timeline. Our color-changing flowers, for example, were designed on a solid foundation of basic research spanning 30 years, a known pathway, and team of petunia color experts, and a lot of that planning involved ways to overcome known unknowns. We needed a clear idea about what we wanted to achieve before we could develop a practical technical plan to accomplish it.

So, what do you want your dragon to look like?

  • Does the dragon need wings? Scales? Teeth?
  • Does it have to breathe fire?
  • Does the dragon need four legs or can it get by with two?
  • How big should the dragon be?

dragon
There is an exceptional flash game by Wyndbain where you can build your dragon with wings, claws, and 8 pages (!) of horn styles. However it has a terrible ad that plays when I embed it, so you’ll have to click here to use it.

Dragons are mythical creatures so we have a pretty blank slate. We can focus on the features we need to meet our goals — We don’t need to achieve full Game of Thrones functionality in the first iteration. You’re not Daenerys. If you had a full grown firebreathing dragon, at some point it would just set fire to your house and eat the neighbor kid.

Let’s starting by engineering something that looks like a dragon – something small, something that smells of sulfur once in a while. I’m thinking that the primary requirements are wings and a scaled body. Jointed wings – even if they can’t be used to fly – and a body covered in scales are pretty unmistakeable as a dragon hallmark. Everything else can be negotiated.

Disagree? Share your thoughts in the comments.

14 Jan

How to make a dragon – a step by step bioengineering guide

Revolution Bio is at the top of the search results for the terms ‘crazy bioengineering dragon idea.’ While we are making color-changing flowers, not dragons, I’m pretty excited that people looking for incredible advances in biotechnology find us on the front page. So I’m going to take a cue from XKCD’s “What If” blag and answer the question “What would it take to engineer a dragon?”

Trogdor the Burninator - Homestar Runner“Feel free to follow along with my simple step-by-step instruction.” – Strongbad, Homestar Runner

Part 1 – Should we bioengineer a dragon?

Before starting in on our dragon, we should carefully consider whether or not this project has a function beyond “Well that’s cool.” Modifying a living creature in any way, shape, or form has ethical implications – conventional breeding included. Animals have been domesticated and bred for millenia, and now broiler chickens have such disproportionate amounts of white meat that they can’t stand up . Soldiers and police rely on German Shepherds, but these dogs often have terrible hip problems as a result of their pedigree. There needs to be a compelling and comprehensive answer as to why we should engineer an organism.

Our reason for engineering a dragon doesn’t have to be as direct as “I need to regain the Iron Throne”, though — maybe there are significant technical advances that could be made by starting this project, like better understanding the developmental processes that result in wings and scales and fire-breathing. Maybe this is an engaging way to get the public intrigued in science, technology and the way the two are rapidly evolving. Maybe there are a LOT of consumers that want a pet dragon, or lap giraffes, or housecats that look like lions and cheetahs, and we just didn’t know it until someone asked the question. (Is this you? Support consumer biotechnology and sign up for our mailing list here).

A lap giraffe - luxury consumer biotechnology
Admit it, you signed up for the waiting list.

Let’s take a close look at why we need a dragon, and then determine whether bioengineering is the best possible solution to those needs.

In some cases, there may be an existing solution that could take the place of bioengineering a dragon. Are you looking for an animal companion that will keep down your goat population? Why not a golden eagle instead? Maybe you want a trusty steed that you can rely on in dangerous situations. Horses might be a little tame for your taste, but a war zebra or an elephant might do just as well.

blog post trogdor part 1 dragon v 747
Left: Airplane, Right: Dragon

It’s also unlikely that bioengineering will be the quick and inexpensive way to accomplish your goal. If your primary goal is personal flight transportation, we have some incredible aeronautical engineering marvels out there in the shape of airplanes and helicopters, and human powered gliders also exist. At today’s level of technology, there is no possible way that making this dragon will be in any way cheaper or faster than mechanical flight. An animal that a human can ride through the air is a tall order.

Right now “because they’re cool” is probably still at the top of your list of reasons to bioengineer a dragon. The cool factor drives a lot of product development in everything from fashion to electronics. Dragons, the imaginary ones that don’t exist, are pretty amazing — but to get from zero to dragon, you are going to have to do a lot of basic research and testing. And when we’re talking about engineering a living creature and all its complexities, this can yield ugly, not-quite-dragon, results.

So, is it worth it? Should we bioengineer a dragon? Share your thoughts below!

Part II – Design